Neuroserpin Antibody

Product Specifications

Background

Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.

NCBI Gene ID

5274

Swiss Prot

Q99574

Accession Number

NP_001116224.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Neuroserpin antibody was raised against a peptide sequence around aa.402~406 (T-S-G-H-D) derived from Human Neuroserpin.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Stem Cell

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

55 kDa

Specificity

This antibody detects endogenous level of total Neuroserpin protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

SERPINI1

NCBI Official Name

Serpin peptidase inhibitor, clade I (neuroserpin), member 1

NCBI Organism

Homo sapiens

Background Reference 01

Davis R. L., Shrimpton A. E., Holohan P. D., Bradshaw C., Feiglin D., Collins G. H., Sonderegger P., Kinter J., Becker L. M., Lacbawan F., Nature 401:376-379 (1999)