CD10 Antibody

Product Specifications

Background

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

NCBI Gene ID

4311

Swiss Prot

P08473

Accession Number

NP_000893.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

CD10 antibody was raised against a peptide sequence around aa.6~10 (S-Q-M-D-I) derived from Human CD10.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

100 kDa

Specificity

This antibody detects endogenous level of total CD10 protein.

Applications Notes

Western Blot: 1:500

Symbol

MME

NCBI Official Name

Membrane metallo-endopeptidase

NCBI Organism

Homo sapiens

Background Reference 01

Yandle T. G., Brennan S. O., Espiner E. A., Nicholls M. G., Richards A. M. Peptides 10:891-894 (1989) Rice G. I., Thomas D. A., Grant P. J., Turner A. J., Hooper N. M. Biochem. J. 383:45-51 (2004) Morisaki N., Moriwaki S., Sugiyama-Nakagiri Y., Haketa K., Takema Y., Imokawa G. J. Biol. Chem. 285:39819-39827 (2010)