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N Cadherin (CD325) Antibody

Product Specifications

Background

Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density

NCBI Gene ID

1000

Swiss Prot

P19022

Accession Number

NP_001783.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

N-Cadherin (CD325) antibody was raised against a peptide sequence around aa.800~804 (A-I-K-P-V) derived from Human N-Cadherin.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

140 kDa

Specificity

This antibody detects endogenous level of total N-Cadherin protein.

Applications Notes

Western Blot: 1:500

Symbol

CDH2

NCBI Official Name

Cadherin 2, type 1, N-cadherin (neuronal)

NCBI Organism

Homo sapiens

Background Reference 01

Bhatt A. S. et. al (2005) Oncogene 24:5333-5343Salomon D. et. al (1992) J. Cell Sci. 102:7-17The MGC Project Team (2004) Genome Res. 14:2121-2127

Other Product Names

CDHN, NCAD, CD325, CDw325, CDH2, CDCN

Tested Applications

WB

Protein ID

14589889

Physical Properties

Liquid

Curated Selection

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