FBXL3 Antibody

Product Specifications

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.

NCBI Gene ID

50789

Swiss Prot

Q8C4V4

Accession Number

NP_056637.1

Host

Rabbit

Reactivity

Mouse

Immunogen

FBXL3 antibody was raised against a peptide sequence around aa.1~5 (M-K-R-G-G) derived from mouse FBXL3 .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

49 kDa

Specificity

This antibody detects endogenous levels of total FBXL3 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

Fbxl3

NCBI Official Name

F-box and leucine-rich repeat protein 3

NCBI Organism

This antibody was raised against a peptide sequence around aa.1~5 (M-K-R-G-G) derived from mouse FBXL3

Background Reference 01

"Winston J. T., et al. (1999) Curr. Biol. 9:1180-1182. Carninci P. et al. (2005) Science 309:1559-1563. The MGC Project Team, (2004) Genome Res. 14:2121-2127.