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MCL1 Antibody

Product Specifications

Background

Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

NCBI Gene ID

4170

Swiss Prot

Q07820

Accession Number

NP_068779.1

Host

Rabbit

Reactivity

Human

Immunogen

MCL1 antibody was raised against a peptide sequence around aa.148~152 (N-N-T-S-T) derived from Human MCL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

42 kDa

Specificity

This antibody detects endogenous level of total MCL1 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

MCL1

NCBI Official Name

Myeloid cell leukemia sequence 1 (BCL2-related)

NCBI Organism

Homo sapiens

Background Reference 01

Bingle C. D., Craig R. W., Swales B. M., Singleton V., Zhou P., Whyle M. K. B. J. Biol. Chem. 275:22136-22146 (2000)

Other Product Names

TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT, TUBB4, TM

Tested Applications

WB

Protein ID

11386165

Physical Properties

Liquid

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