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ASPSCR1 Antibody

Product Specifications

Background

Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.

NCBI Gene ID

79058

Swiss Prot

Q9BZE9

Accession Number

NP_076988.1

Host

Rabbit

Reactivity

Human

Immunogen

ASPSCR1 antibody was raised against a peptide sequence around aa.303 ~307 (P-Q-Q-E-Q) derived from Human ASPSCR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

70 - 75 kDa

Specificity

This antibody detects endogenous levels of total ASPSCR1 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

ASPSCR1

NCBI Official Name

Alveolar soft part sarcoma chromosome region, candidate 1

NCBI Organism

Homo sapiens

Background Reference 01

Ladanyi, M. et al. (2001) Oncogene 20, 48-57. Bogan, J. S. et al. (2003) Nature 425, 727-33. Yu, C. et al. (2007) J Biol Chem 282, 7710-22.

Other Product Names

TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9, ASPCR1, HSP27, HSP28, TUG

Tested Applications

WB

Protein ID

13129078

Physical Properties

Liquid

Curated Selection

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