Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Fas Antibody

Product Specifications

Background

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro) .

NCBI Gene ID

355

Swiss Prot

P25445

Accession Number

NP_000034.1

Host

Rabbit

Reactivity

Human

Immunogen

Fas antibody was raised against a peptide sequence around aa.323~327 (E-N-S-N-F) derived from human Fas .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=79-640

Calculated Molecular Weight

40 - 50 kDa

Specificity

This antibody detects endogenous level of total Fas protein.

Applications Notes

Western Blot: 1:1000

Symbol

FAS

NCBI Official Name

Fas cell surface death receptor

NCBI Organism

Homo sapiens

Background Reference 01

Hahne, M. et al. (1995) Int Immunol 7, 1381-6. Nagata, S. (1997) Cell 88, 355-65. Green, D. R. and Ferguson, T. A. (2001) Nat Rev Mol Cell Biol 2, 917-24.

Other Product Names

APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, RP11-399O19.9, IKBE, FASLG receptor, Apoptosis-mediating surface antigen FAS, Apo-1 antigen

Tested Applications

WB

Protein ID

4507583

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

3- (4-Ethylphenyl) -1- (o-tolyl) -1H-pyrazole-4-carboxylic acid
OR84470-01 100 mg

3- (4-Ethylphenyl) -1- (o-tolyl) -1H-pyrazole-4-carboxylic acid

Ask
View Details
3- (4-Ethylphenyl) -1- (o-tolyl) -1H-pyrazole-4-carboxylic acid
OR84470-02 250 mg

3- (4-Ethylphenyl) -1- (o-tolyl) -1H-pyrazole-4-carboxylic acid

Ask
View Details
Anti-ACTH (Adrenocorticotrophic Hormone) (N-Terminal) (Pituitary Marker) (r57)
BNUB1380-500 500 µL

Anti-ACTH (Adrenocorticotrophic Hormone) (N-Terminal) (Pituitary Marker) (r57)

Ask
View Details
Human Defensin Beta 126 (DEFb126) ELISA Kit
EKN44776-01 48 Tests

Human Defensin Beta 126 (DEFb126) ELISA Kit

Ask
View Details
Human Defensin Beta 126 (DEFb126) ELISA Kit
EKN44776-02 96 Tests

Human Defensin Beta 126 (DEFb126) ELISA Kit

Ask
View Details
Human Defensin Beta 126 (DEFb126) ELISA Kit
EKN44776-03 5x 96 Tests

Human Defensin Beta 126 (DEFb126) ELISA Kit

Ask
View Details