H2B Antibody
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
NCBI Gene ID
8349
Swiss Prot
P33778
Accession Number
NP_003519.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
H2B antibody was raised against a peptide sequence around aa.41~45 (Y-V-Y-K-V) derived from Human H2B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
14 kDa
Specificity
This antibody detects endogenous level of total H2B protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
HIST2H2BE
NCBI Official Name
Histone cluster 2, H2be
NCBI Organism
Homo sapiens
Background Reference 01
Borchert GM, et al. (2010) PLoS One. 5 (7) : e11641. Pennini ME, et al. (2010) PLoS Pathog. 6 (7) : e1000995. Lu C, et al. (2010) Sci China Life Sci. 53 (6) : 663-8.
Other Product Names
H2B, H2BQ, GL105, H2B.1, H2BFQ, H2BGL105
Tested Applications
WB
Protein ID
4504277
Physical Properties
Liquid
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