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H2B Antibody

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

NCBI Gene ID

8349

Swiss Prot

P33778

Accession Number

NP_003519.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

H2B antibody was raised against a peptide sequence around aa.41~45 (Y-V-Y-K-V) derived from Human H2B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=79-638

Calculated Molecular Weight

14 kDa

Specificity

This antibody detects endogenous level of total H2B protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

HIST2H2BE

NCBI Official Name

Histone cluster 2, H2be

NCBI Organism

Homo sapiens

Background Reference 01

Borchert GM, et al. (2010) PLoS One. 5 (7) : e11641. Pennini ME, et al. (2010) PLoS Pathog. 6 (7) : e1000995. Lu C, et al. (2010) Sci China Life Sci. 53 (6) : 663-8.

Other Product Names

H2B, H2BQ, GL105, H2B.1, H2BFQ, H2BGL105

Tested Applications

WB

Protein ID

4504277

Physical Properties

Liquid

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