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Melanoma associated antigen D1 Antibody

Product Specifications

Background

Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.

NCBI Gene ID

94275

Swiss Prot

Q9QYH6

Accession Number

NP_062765.1

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Melanoma-associated antigen D1 antibodyPeptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

95 kDa

Specificity

This antibody detects endogenous level of total Melanoma-associated antigen D1 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

Maged1

NCBI Official Name

Melanoma antigen, family D, 1

NCBI Organism

Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.

Background Reference 01

Zhao Z, et al. (2002) Sci China C Life Sci. 45 (4) : 412-20. Shen WG, et al. (2007) Cell Commun Adhes. 14 (1) : 21-31. Cheresh DA, et al. (1984) J Biol Chem. 259 (12) : 7453-9.

Other Product Names

NRAGE, Dlixin, Dlxin1, Dlxin-1, MAGE-D1, mFLJ00163, DXBwg1492e, 2810433C11Rik, 5430405L04Rik, MAGED1

Tested Applications

WB

Protein ID

9789935

Physical Properties

Liquid

Frequently Asked Questions

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