Lymphatic vessel endothelial hyaluronic acid receptor 1 Antibody

Product Specifications

Background

Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS) . May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

NCBI Gene ID

10894

Swiss Prot

Q9Y5Y7

Accession Number

NP_006682.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Lymphatic vessel endothelial hyaluronic acid receptor 1 antibody was raised against a peptide sequence around aa.271~275 (K-N-Q-Q-K) derived from Human Lymphatic vessel endothelial hyaluronic acid receptor 1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

40 kDa

Specificity

This antibody detects endogenous level of total Lymphatic vessel endothelial hyaluronic acid receptor 1 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

LYVE1

NCBI Official Name

Lymphatic vessel endothelial hyaluronan receptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Heindl LM, et al. (2010) Ophthalmology. 117 (2) : 334-42. He P et al. (2006) Lin Chuang Er Bi Yan Hou Ke Za Zhi. 20 (18) : 828-30, 833. Lim HY, et al. (2009) Am J Pathol. 175 (3) : 1328-37.