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PRL 3 Antibody

Product Specifications

Background

Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.

NCBI Gene ID

11156

Swiss Prot

O75365

Accession Number

NP_116000

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

PRL-3 antibody was raised against a peptide sequence around aa. 161-166 (K-D-P-H-T) derived from Human PTP4A3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

22 kDa

Specificity

This antibody detects transfected PRL-3 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

PTP4A3

NCBI Official Name

Protein tyrosine phosphatase type IVA, member 3

NCBI Organism

Homo sapiens

Background Reference 01

Matter W. F. et. al. Biochem. Biophys. Res. Commun. 283:1061-1068 (2001) Wang J. et. al. J. Biol. Chem. 277:46659-46668 (2002)

Other Product Names

PRL3, PRL-3, PRL-R, HDACL1, CDA07, protein tyrosine phosphatase type IVA, PRL3, PTP4A3

Tested Applications

WB

Protein ID

14589856

Physical Properties

Liquid

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