Synaptotagmin (Ab 309) Antibody

Product Specifications

Background

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse

NCBI Gene ID

6857

Swiss Prot

P21579

Accession Number

NP_001129277.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synaptotagmin (Ab-309) antibody was raised against a peptide sequence around aa.307~311 (G-L-S-D-P) derived from Human Synaptotagmin.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

60 - 65 kDa

Specificity

This antibody detects endogenous level of total Synaptotagmin protein.

Applications Notes

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Symbol

SYT1

NCBI Official Name

Synaptotagmin I

NCBI Organism

Homo sapiens

Background Reference 01

Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11; 105 (10) : 3992-7. Cnops L, et al. Cereb Cortex. 2008 May; 18 (5) : 1221-31. Lynch KL, et al. Mol Biol Cell. 2007 Dec; 18 (12) : 4957-68.