CaMKII (Ab 286) Antibody

Product Specifications

Background

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity

NCBI Gene ID

94032

Swiss Prot

P11798

Accession Number

NP_150284.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

CaMKII (Ab-286) antibody was raised against a peptide sequence around aa.284~288 (Q-E-T-V-D) derived from Human CaMKII.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

50 kDa

Specificity

This antibody detects endogenous level of total CaMKII protein.

Applications Notes

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Symbol

CAMK2N2

NCBI Official Name

Calcium/calmodulin-dependent protein kinase II inhibitor 2

NCBI Organism

Homo sapiens

Background Reference 01

J Bossuyt, K Helmstadter, X Wu, et al. (2008) Ca2+/Calmodulin-Dependent Protein Kinase II {delta} and Protein Kinase D Overexpression Reinforce - Circulation Research, 102 (6) : 695-702.