P44 / 42 MAP Kinase (Ab 202) Antibody

Product Specifications

Background

Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2) . Phosphorylates SPZ1

NCBI Gene ID

5595

Swiss Prot

P27361

Accession Number

NP_001035145.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

P44/42 MAP Kinase (Ab-202) antibody was raised against a peptide sequence around aa. 200~204 (F-L-T-E-Y) derived from Human p44/42 MAP Kinase.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

42, 44 kDa

Specificity

This antibody detects endogenous level of total p44/42 MAP Kinase protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

MAPK3

NCBI Official Name

Mitogen-activated protein kinase 3

NCBI Organism

Homo sapiens

Background Reference 01

TETE HANNKEN, et al. (2000) Am Soc Nephrol 11:1387-1397Omar D. PerezNature et al. (2002) Biotechnology 20: 155 - 162 Jingui Yu, et al. (2005) Anesth Analg 101: 315-321Hironobu Ihn et al. (2000) Immunology 165: 2149-2155