C Kit (Ab 721) Antibody

Product Specifications

Background

This is the receptor for stem cell factor (mast cell growth factor) . It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)

NCBI Gene ID

3815

Swiss Prot

P11362

Accession Number

NP_000213.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

C-Kit (Ab-721) antibody was raised against a peptide sequence around aa.719~723 (N-E-Y-M-D) derived from Human c-Kit.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

145 kDa

Specificity

This antibody detects endogenous level of total c-Kit protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

KIT

NCBI Official Name

V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

NCBI Organism

Homo sapiens

Background Reference 01

Kimura W, et al. (2007) Hepatogastroenterology. 54 (80) : 2203-8. Naeem M, et al. (2002) Hum Pathol. 33 (12) : 1182-7. Jankulovski N, et al. (2006) Prilozi. 27 (2) : 59-70.