Ezrin (Ab 567) Antibody
Product Specifications
Background
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
NCBI Gene ID
7430
Swiss Prot
P15311
Accession Number
NP_001104547.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ezrin (Ab-567) antibody was raised against a peptide sequence around aa. 565~569 (Y-K-T-L-R) derived from Human Ezrin.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
81 kDa
Specificity
This antibody detects endogenous level of total Ezrin protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
EZR
NCBI Official Name
Ezrin
NCBI Organism
Homo sapiens
Background Reference 01
Zhou R, et al. (2005) J Cell Sci: 118 (Pt 19) : 4381-91. Shiue H, et al. (2005) J Biol Chem: 280 (2) : 1688-95. Zhao H, et al. (2004) Proc Natl Acad Sci U S A: 101 (25) : 9485-90. Fievet BT, et al. (2004) J Cell Biol: 164 (5) : 653-9.
Other Product Names
CVL, CVIL, VIL2, HEL-S-105, Cytovillin, EZRI, Villin 2, p81
Tested Applications
WB
Protein ID
161702986
Physical Properties
Liquid
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