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Ephrin B2 (Ab 330) Antibody

Product Specifications

Background

Ephrin-B2 encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a lycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.

NCBI Gene ID

1948

Swiss Prot

P52799

Accession Number

NP_004084.1

Host

Rabbit

Reactivity

Human

Immunogen

Ephrin-B2 (Ab-330) antibody was raised against a peptide sequence around aa.328~332 (N-I-Y-Y-K) derived from Human Ephrin B (ephrin-B2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

37 kDa

Specificity

This antibody detects endogenous level of total Ephrin-B2 protein.

Applications Notes

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Symbol

EFNB2

NCBI Official Name

Ephrin-B2

NCBI Organism

Homo sapiens

Background Reference 01

Chrencik JE, et al. (2006) J Biol Chem;281 (38) : 28185-28192. Kertesz N, et al. (2006) Blood; 107 (6) : 2330-2338. Noren NK, et al. (2004) Proc Natl Acad Sci USA; 101 (15) : 5583-5588.

Other Product Names

HTKL, EPLG5, Htk-L, LERK5, ON, EFNB2, HTKL, LERK5

Tested Applications

WB, IF

Protein ID

4758250

Physical Properties

Liquid

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