FKHRL1 (Ab 253) Antibody

Product Specifications

Background

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.

NCBI Gene ID

2309

Swiss Prot

O43524

Accession Number

NP_001446.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

FKHRL1 (Ab-253) antibody was raised against a peptide sequence around aa.251~255 (A-V-S-M-D) derived from Human FKHRL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

97 kDa

Specificity

This antibody detects endogenous level of total FKHRL1 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

FOXO3

NCBI Official Name

Forkhead box O3

NCBI Organism

Homo sapiens

Background Reference 01

Brunet A., Bonni A., Zigmond M. J., Lin M. Z., Juo P., Hu L. S., Anderson M. J., Arden K. C., Blenis J., Greenberg M. E. Cell 96:857-868 (1999) Lehtinen M. K., Yuan Z., Boag P. R., Yang Y., Villen J., Becker E. B. E., DiBacco S., de la Iglesia N., Gygi S. P., Blackwell T. K., Bonni A. Cell 125:987-1001 (2006)