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Vav (Ab 174) Antibody

Product Specifications

Background

Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.

NCBI Gene ID

7409

Swiss Prot

P15498

Accession Number

NP_005419.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Vav (Ab-174) antibody was raised against a peptide sequence around aa. 172~176 (E-I-Y-E-D) derived from Human Vav.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

95 kDa

Specificity

This antibody detects endogenous level of total Vav protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

VAV1

NCBI Official Name

Vav 1 guanine nucleotide exchange factor

NCBI Organism

Homo sapiens

Background Reference 01

Amarasinghe GK, et al. (2005) Biochemistry; 44 (46) : 15257-68. Charvet C, et al. (2005) J Biol Chem; 280 (15) : 15289-99. Miura-Shimura Y, et al. (2003) J Biol Chem; 278 (40) : 38495-504. Kuhne MR, et al. (2000) J Biol Chem; 275 (3) : 2185-90.

Other Product Names

VAV

Tested Applications

WB

Protein ID

7108367

Physical Properties

Liquid

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