Myosin Light Chain 2 (Ab 18) Antibody

Product Specifications

Background

Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion

NCBI Gene ID

10627

Swiss Prot

P19105

Accession Number

NP_006462.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Myosin Light Chain 2 (Ab-18) antibody was raised against a peptide sequence around aa.16~20 (A-T-S-N-V) derived from Human Myosin Light Chain 2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

18 kDa

Specificity

This antibody detects endogenous level of total Myosin Light Chain 2 protein.

Applications Notes

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Symbol

MYL12A

NCBI Official Name

Myosin, light chain 12A, regulatory, non-sarcomeric

NCBI Organism

Homo sapiens

Background Reference 01

Janiak A, et al. (2006) Mol Biol Cell. Apr; 17 (4) : 1606-1619. Croft DR, et al. (2006) Mol Cell Biol. 2 Jun; 26 (12) : 4612-4627Li Z, et al. (2006) Mol Cell Biol. Jun; 26 (11) : 4240-4256