Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Tau (Ab 404) Antibody

Product Specifications

Background

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

NCBI Gene ID

4137

Swiss Prot

P10636

Accession Number

NP_001116538.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Tau (Ab-404) antibody was raised against a peptide sequence around aa. 402~406 (D-T-S-P-R) derived from Human Tau.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=79-543

Calculated Molecular Weight

48, 62, 78 kDa

Specificity

This antibody detects endogenous level of total Tau protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

MAPT

NCBI Official Name

Microtubule-associated protein tau

NCBI Organism

Homo sapiens

Background Reference 01

Li G, Yin H, et. al . (2004) J Biol Chem ; 279 (16) : 15938-45. Noble W, et al. (2003) Neuron ; 38 (4) : 555-65. Giasson BI, et al. (2002) . Biochemistry; 41 (51) : 15376-87. Lee G., et. al. (1989) . Neuron 2:1615-1624. Andreadis A. et. al. (1992) Biochemistry 31:10626-10633.

Other Product Names

TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, Neurofibrillary tangle protein, Paired helical filament-tau

Tested Applications

WB

Protein ID

178557734

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

OR4G6P Protein Lysate (Human) with C-Ha Tag
35227031 100 μg

OR4G6P Protein Lysate (Human) with C-Ha Tag

Ask
View Details
NUBP2 (NM_001284502) Human Tagged ORF Clone
RC236690 10 µg

NUBP2 (NM_001284502) Human Tagged ORF Clone

Ask
View Details
HBV Monoclonal Antibody
VAnt-Wyb053 Each

HBV Monoclonal Antibody

Ask
View Details
Dda1 siRNA Oligos set (Rat)
17767176 3 x 5 nmol

Dda1 siRNA Oligos set (Rat)

Ask
View Details
Atp6v1c2 (NM_133699) Mouse Tagged ORF Clone Lentiviral Particle
MR206810L4V 200 µL

Atp6v1c2 (NM_133699) Mouse Tagged ORF Clone Lentiviral Particle

Ask
View Details
Recombinant Histone H3K36me3 (MLA)
MBS388034-01 0.05 mg

Recombinant Histone H3K36me3 (MLA)

Ask
View Details