Synapsin (phospho Ser549) Antibody
Product Specifications
Background
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level
NCBI Gene ID
20964
Swiss Prot
O88935
Accession Number
NP_038708.3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synapsin (phospho-Ser549) antibody was raised against a peptide sequence around phosphorylation site of serine 549 (P-A-S (p) -P-S) derived from Rat Synapsin.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific, Neuroscience
Purification
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
78 kDa
Specificity
This antibody detects endogenous level of Synapsin only when phosphorylated at serine 549.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
Syn1
NCBI Official Name
Synapsin I
NCBI Organism
Rattus
Background Reference 01
Greengard, P. (1987) Mol Neurobiol 1, 81-119. Hosaka, M. et al. (1999) Neuron 24, 377-87.
Other Product Names
Syn-1, P53, Syn-1, synapsin I
Tested Applications
WB
Protein ID
160707901
Physical Properties
Liquid
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