EGFR (phospho Tyr1197) Goat Polyclonal Antibody

Product Specifications

Background

Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia

NCBI Gene ID

1956

Swiss Prot

P00533

Accession Number

NP_005219.2

Host

Goat

Reactivity

Human, Mouse, Rat

Immunogen

EGFR (phospho-Tyr1197) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1197 (A-E-Y (p) -L-R) derived from Human EGFR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

175 kDa

Specificity

This antibody detects endogenous level of total EGFR protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

EGFR

NCBI Official Name

Epidermal growth factor receptor

NCBI Organism

Homo sapiens

Background Reference 01

Corbalan-Garcia S, et al. (1996) Mol Cell Biolt; 16 (10) : 5674-5682Kanner SB, et al. (1991) Mol Cell Biol; 11 (2) : 713-720Wu TT, et al. (1998) Mol Biol Cell; 9 (7) : 1661-1674O’Rourke DM, et al. (1997) Proc Natl Acad Sci U S A; 94 (7) : 3250-3255Goldstein DJ, et al. (1994) J Virol; 68 (7) : 4432-4441