Smad2 (phospho Ser467) Antibody
Product Specifications
Background
Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD) . May act as a tumor suppressor in colorectal carcinoma.
NCBI Gene ID
4087
Swiss Prot
Q15796
Accession Number
NP_001003652.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Smad2 (Phospho-Ser467) antibody was raised against a peptide sequence around phosphorylation site of serine 467 (C-S-S-M-S (p) ) derived from Human Smad2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
60 kDa
Specificity
This antibody detects endogenous level of Smad2 only when phosphorylated at serine 467.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
SMAD2
NCBI Official Name
SMAD family member 2
NCBI Organism
Homo sapiens
Background Reference 01
Sang Gyun Kim et al. (2004) Mol Biol Cell. February; 15 (2) : 420–434. Rebecca A. Randall et al. (2004) Mol Cell Biol. February; 24 (3) : 1106–1121. Kimberly A Brown et al. (2004) Breast Cancer Res. ; 6 (3) : R215–R231.
Other Product Names
JV18, MADH2, MADR2, JV18-1, hMAD-2, hSMAD2, FAK, FAK1, Mad-related protein 2, Mothers against DPP homolog 2
Tested Applications
WB
Protein ID
51173730
Physical Properties
Liquid
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