Synapsin (phospho Ser9) Antibody
Product Specifications
Background
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
NCBI Gene ID
6853
Swiss Prot
P17600
Accession Number
NP_008881.2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synapsin (Phospho-Ser9) antibody was raised against a peptide sequence around phosphorylation site of serine 9 (R-L-S (p) -D-S) derived from Human SYN1/synapsin.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific, Neuroscience
Purification
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=79-487
Calculated Molecular Weight
77 kDa
Specificity
This antibody detects endogenous level of synapsin only when phosphorylated at serine 9.
Applications Notes
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Symbol
SYN1
NCBI Official Name
Synapsin I
NCBI Organism
Homo sapiens
Background Reference 01
Diviya Sinha, et, al. (2005) Am J Physiol Renal Physiol ; 288: F703 - F713. Franco Onofri, et, al. (2000) J. Biol. Chem ; 275: 29857. Dario Bonanomi, et, al. (2005) J. Neurosci; 25: 7299 - 7308. Hiroshi Tokumitsu, et, al. (2005) J. Biol. Chem ; 280: 35108 - 35118.
Other Product Names
SYNI, SYN1a, SYN1b, CDKN2
Tested Applications
WB, IF
Protein ID
19924099
Physical Properties
Liquid
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