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Met (phospho Tyr1234) Antibody

Product Specifications

Background

Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

NCBI Gene ID

4233

Swiss Prot

P08581

Accession Number

NP_000236.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Met (Phospho-Tyr1234) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1234 (K-E-Y (p) -Y-S) derived from Human Met.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=79-476

Calculated Molecular Weight

156 kDa

Specificity

This antibody detects endogenous level of Met only when phosphorylated at tyrosine 1234.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

MET

NCBI Official Name

Met proto-oncogene

NCBI Organism

Homo sapiens

Background Reference 01

Gherardi E. et al. (2003) . Proc Natl Acad Sci U S A. 100 (21) : 12039-12044. Shiu SH. et al. (2001) Proc Natl Acad Sci U S A. 98 (19) : 10763-10768. Hughes AL. et al. (2001) Genome Res. 11 (5) : 771-780. Onuchic LF. et al. (2002) Am J Hum Genet. 70 (5) : 1305-1317.

Other Product Names

HGFR, AUTS9, RCCP2, c-Met, ACDC, ACRP30, APM1, GBP28, HGF receptor, receptor, Met proto-oncogene tyrosine kinase, c-met, kinase Met

Tested Applications

WB

Protein ID

42741655

Physical Properties

Liquid

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