Ezrin (phospho Thr567) Antibody
Product Specifications
Background
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
NCBI Gene ID
7403
Swiss Prot
P15311
Accession Number
NP_001104547.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ezrin (Phospho-Thr567) antibody was raised against a peptide sequence around phosphorylation site of threonine 567 (Y-K-T (p) -L-R) derived from Human Ezrin.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=79-471
Calculated Molecular Weight
81 kDa
Specificity
This antibody detects endogenous level of Ezrin only when phosphorylated at threonine 567.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
KDM6A
NCBI Official Name
Lysine (K) -specific demethylase 6A
NCBI Organism
Homo sapiens
Background Reference 01
Zhou R, et al. (2005) J Cell Sci: 118 (Pt 19) : 4381-91Shiue H, et al. (2005) J Biol Chem: 280 (2) : 1688-95Zhao H, et al. (2004) Proc Natl Acad Sci U S A: 101 (25) : 9485-90Fievet BT, et al. (2004) J Cell Biol: 164 (5) : 653-9
Other Product Names
UTX, KABUK2, bA386N14.2, MEK3, MKK3, PRKMK3, SKK2, Cytovillin, EZRI, VIL2, Villin 2, p81
Tested Applications
WB
Protein ID
161702986
Physical Properties
Liquid
Curated Selection
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