Ephrin B2 (phospho Tyr316) Antibody
Product Specifications
Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
NCBI Gene ID
1948
Swiss Prot
P52799
Accession Number
NP_004084.1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Ephrin-B2 (Phospho-Tyr316) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 316 (P-V-Y (p) -I-V) derived from Human Ephrin-B2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific, Apoptosis, Cancer, Cell Cycle
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
37 kDa
Specificity
This antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 316.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
EFNB2
NCBI Official Name
Ephrin-B2
NCBI Organism
Homo sapiens
Background Reference 01
Chrencik JE, et al. (2006) J Biol Chem;281 (38) : 28185-28192. Kertesz N, et al. (2006) Blood;107 (6) : 2330-2338. Noren NK, et al. (2004) Proc Natl Acad Sci USA;101 (15) : 5583-5588
Other Product Names
HTKL, EPLG5, Htk-L, LERK5, MEK1, PRKMK1, HTKL
Tested Applications
WB
Protein ID
4758250
Physical Properties
Liquid
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