Fc epsilon Receptor I alpha Antibody [FceR1] (PE)
Selected Variant
77-178
Size: 0.1 mg
Product Specifications
Background
The Mar-1 monoclonal antibody binds to the Fc epsilon Receptor I alpha subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.The Fc epsilon Receptor I alpha subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs) . The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.
NCBI Gene ID
2205
Swiss Prot
P12319
Host
Hamster
Reactivity
Mouse
Clonality
Monoclonal
Clone
FceR1
Conjugation
PE
Type
Primary Antibodies
Field of Research
Innate Immunity
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Armenian Hamster IgG
Specificity
The Mar-1 monoclonal antibody binds to the Fc epsilon Receptor I alpha subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily.
Symbol
FCER1A
NCBI Official Name
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
NCBI Organism
Homo sapiens
Other Product Names
FCE1A, FcER, FCER1A
Tested Applications
Flow
Physical Properties
Liquid
Price
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