NK1.1 Antibody [PK136]
Product Specifications
Background
The PK136 monoclonal antibody is specific for the mouse NK1.1, a receptor from the killer cell lectin-like receptor (KLR) family. Nk1.1 is an antigen encoded by the Klrb1c/NKR-P1C gene expressed by the natural killer cells of some selected strains of mice (C57BL, FVB/N, NZB) and encoded by the Klrb1b/NKR-P1B gene expressed on Swiss NIH and SJL mice. Pk136 binds to an epitope common to NKR-P1B and NKR-P1C.The Klrb1 is a family of type II transmembrane C-type lectin receptors. Klrb1c activates the NK-cell cytotoxicity, while Klrb1b inhibits it. PK136 is useful in defining the NK cells and the rare population of NK-T lymphocytes and specific cultured monocytes.
NCBI Gene ID
17059
Swiss Prot
P27814
Host
Mouse
Reactivity
Mouse
Clonality
Monoclonal
Clone
PK136
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=77-153
Fragment
Mouse IgG2a, kappa
Specificity
The PK136 monoclonal antibody is specific for the mouse NK1.1, a receptor from the killer cell lectin-like receptor (KLR) family.
Symbol
Klrb1c
NCBI Official Name
Killer cell lectin-like receptor subfamily B member 1C
NCBI Organism
Mus musculus
Other Product Names
Nk1, Ly59, Nk-1, CD161, Ly-59, Ly55c, NK1.1, NKRP1, Nk1.2, NK-RP1, Nk-1.2, Nkrp1c, ly-55c, NKRP140, AI462337, NKR-P1.9, Klrb1c
Tested Applications
Flow, Functional Assays, IHC, IF, IP
Physical Properties
Liquid
Curated Selection
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