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NK1.1 Antibody [PK136]

Product Specifications

Background

The PK136 monoclonal antibody is specific for the mouse NK1.1, a receptor from the killer cell lectin-like receptor (KLR) family. Nk1.1 is an antigen encoded by the Klrb1c/NKR-P1C gene expressed by the natural killer cells of some selected strains of mice (C57BL, FVB/N, NZB) and encoded by the Klrb1b/NKR-P1B gene expressed on Swiss NIH and SJL mice. Pk136 binds to an epitope common to NKR-P1B and NKR-P1C.The Klrb1 is a family of type II transmembrane C-type lectin receptors. Klrb1c activates the NK-cell cytotoxicity, while Klrb1b inhibits it. PK136 is useful in defining the NK cells and the rare population of NK-T lymphocytes and specific cultured monocytes.

NCBI Gene ID

17059

Swiss Prot

P27814

Host

Mouse

Reactivity

Mouse

Clonality

Monoclonal

Clone

PK136

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=77-152

Fragment

Mouse IgG2a, kappa

Specificity

The PK136 monoclonal antibody is specific for the mouse NK1.1, a receptor from the killer cell lectin-like receptor (KLR) family.

Symbol

Klrb1c

NCBI Official Name

Killer cell lectin-like receptor subfamily B member 1C

NCBI Organism

Mus musculus

Other Product Names

Nk1, Ly59, Nk-1, CD161, Ly-59, Ly55c, NK1.1, NKRP1, Nk1.2, NK-RP1, Nk-1.2, Nkrp1c, ly-55c, NKRP140, AI462337, NKR-P1.9, Klrb1c

Tested Applications

Flow, IP

Physical Properties

Liquid

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