Foxp3 Antibody [3G3] (PE)
Product Specifications
Background
The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression.Mutations of Foxp3 result in the “scurfy” mice phenotype.
NCBI Gene ID
20371
Swiss Prot
Q99JB6
Host
Mouse
Reactivity
Mouse
Clonality
Monoclonal
Clone
3G3
Conjugation
PE
Type
Primary Antibodies
Field of Research
Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=77-149
Fragment
Mouse IgG1, kappa
Specificity
The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors.
Symbol
Foxp3
NCBI Official Name
Forkhead box P3
NCBI Organism
Mus musculus
Other Product Names
Sf, JM2, scurfin, Foxp3
Tested Applications
Flow
Physical Properties
Liquid
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