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IL-12/IL-23 p40 Antibody [C17.8] (PE)

Product Specifications

Background

The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer. C17.8 seems to neutralize the activity of mouse IL-12 and IL-23. IL-12 is the p70 heterodimer of p35 and p40, expressed by the macrophages, dendritic cells, and monocytes. The C17.8 antibody cross-reacts with IL-23, since IL-23 also contains one p40 subunit.

NCBI Gene ID

16160

Swiss Prot

P43432

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

C17.8

Conjugation

PE

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Rat IgG2a, kappa

Specificity

The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer.

Symbol

Il12b

NCBI Official Name

Interleukin 12b

NCBI Organism

Mus musculus

Other Product Names

P40, Il-12b, Il12p40, Il-12p40, Il12b

Tested Applications

Flow

Physical Properties

Liquid

Frequently Asked Questions

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