IL-12/IL-23 p40 Antibody [C17.8]
Product Specifications
Background
The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer. C17.8 seems to neutralize the activity of mouse IL-12 and IL-23. IL-12 is the p70 heterodimer of p35 and p40, expressed by the macrophages, dendritic cells, and monocytes. The C17.8 antibody cross-reacts with IL-23, since IL-23 also contains one p40 subunit.
NCBI Gene ID
16160
Swiss Prot
P43432
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Clone
C17.8
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Fragment
Rat IgG2a, kappa
Specificity
The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer.
Symbol
Il12b
NCBI Official Name
Interleukin 12b
NCBI Organism
Mus musculus
Other Product Names
P40, Il-12b, Il12p40, Il-12p40, Il12b
Tested Applications
Flow, Functional Assays, IF, IP, WB, ELISA
Physical Properties
Liquid
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