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LPAM-1 Antibody [DATK32] (Biotin)

Product Specifications

Background

The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mousealpha4beta7 integrin (LPAM-1) . The two subunits of the LPAM-1 heterodimer are the 154 kDa alpha4 and the 130 kDa beta7. Most mature lymphocytes, a subset of bone marrow cells, and some of the thymic cells express the alpha4beta7 integrin heterodimer. alpha4beta7 enhances the transendothelial migration of lymphocytes, and interacts with several ligands (fibronectin, CD106, and MAdCAM-1) . The interaction of DATK32 with the alpha4beta7 induces the alpha4beta7-dependent lymphocyte aggregation and inhibits LPAM-1-dediated cell adhesion.

NCBI Gene ID

16401

Swiss Prot

Q00651

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

DATK32

Conjugation

Biotin

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=77-137

Fragment

Rat IgG2a, kappa

Specificity

The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mousealpha4beta7 integrin (LPAM-1) .

Symbol

Itga4

NCBI Official Name

Integrin alpha 4

NCBI Organism

Mus musculus

Other Product Names

CD49D, Itga4B, Itga4

Tested Applications

Flow

Physical Properties

Liquid

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