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Ly-6G Antibody [RB6-8C5] (PE)

Product Specifications

Background

The RB6-8C5 monoclonal antibody reacts with the mouse Ly-6G (also known as Gr-1) . The Ly-6G protein is a myeloid differentiation antigen of 21-25 kDa, expressed in a regulated manner by the myeloid lineage in the bone marrow, where the level of antigen expression is correlated with the granulocyte maturation and differentiation. In the bone marrow, the antigen is not expressed by the erythroid cells. From the peripheric cells, RB6-8C5 binds with monocytes, neutrophils and eosinophils.As a marker for the mouse monocytes, macrophages and granulocytes, the RB6-8C5 antibody is usually combined with M1/70, a macrophage labeling antibody (Anti-CD11b), for phenotypic analysis.

NCBI Gene ID

546644

Swiss Prot

P35461

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

RB6-8C5

Conjugation

PE

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Rat IgG2b, kappa

Specificity

The RB6-8C5 monoclonal antibody reacts with the mouse Ly-6G (also known as Gr-1) .

Symbol

Ly6g

NCBI Official Name

Lymphocyte antigen 6 complex, locus G

NCBI Organism

Mus musculus

Other Product Names

Gr1, Gr-1, Ly-6G, Ly6g

Tested Applications

Flow

Physical Properties

Liquid

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