Ly-6G Antibody [RB6-8C5]
Product Specifications
Background
The RB6-8C5 monoclonal antibody reacts with the mouse Ly-6G (also known as Gr-1) . The Ly-6G protein is a myeloid differentiation antigen of 21-25 kDa, expressed in a regulated manner by the myeloid lineage in the bone marrow, where the level of antigen expression is correlated with the granulocyte maturation and differentiation. In the bone marrow, the antigen is not expressed by the erythroid cells. From the peripheric cells, RB6-8C5 binds with monocytes, neutrophils and eosinophils.As a marker for the mouse monocytes, macrophages and granulocytes, the RB6-8C5 antibody is usually combined with M1/70, a macrophage labeling antibody (Anti-CD11b), for phenotypic analysis.
NCBI Gene ID
546644
Swiss Prot
P35461
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Clone
RB6-8C5
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Fragment
Rat IgG2b, kappa
Specificity
The RB6-8C5 monoclonal antibody reacts with the mouse Ly-6G (also known as Gr-1) .
Symbol
Ly6g
NCBI Official Name
Lymphocyte antigen 6 complex, locus G
NCBI Organism
Mus musculus
Other Product Names
Gr1, Gr-1, Ly-6G, Ly6g
Tested Applications
Flow, Functional Assays, IHC, IP
Physical Properties
Liquid
Frequently Asked Questions
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