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TIGIT Antibody [1G9] (PE)

Product Specifications

Background

The 1G9 monoclonal antibody specifically binds to the mouse TIGIT, expressed on the T helper cells. While in humans it is expressed also on natural killer cells, Treg cells, memory CD4+ and CD8+ T lymphocytes. TIGIT is not expressed on B cells and is upregulated on CD4+ T cells following activation.TIGIT interacts with CD155, and mediates the interaction between natural killer cells or T lymphocytes with APC and fibroblasts and endothelial cells expressing PVR or PVR-like proteins.

NCBI Gene ID

100043314

Swiss Prot

P86176

Host

Mouse

Reactivity

Mouse

Clonality

Monoclonal

Clone

1G9

Conjugation

PE

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=77-085

Fragment

Mouse IgG1, kappa

Specificity

The 1G9 monoclonal antibody specifically binds to the mouse TIGIT, expressed on the T helper cells.

Symbol

Tigit

NCBI Official Name

T cell immunoreceptor with Ig and ITIM domains

NCBI Organism

Mus musculus

Other Product Names

Vstm3, ENSMUSG00000071552, Tigit

Tested Applications

Flow

Physical Properties

Liquid

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