TIGIT Antibody [1G9] (PE)
Product Specifications
Background
The 1G9 monoclonal antibody specifically binds to the mouse TIGIT, expressed on the T helper cells. While in humans it is expressed also on natural killer cells, Treg cells, memory CD4+ and CD8+ T lymphocytes. TIGIT is not expressed on B cells and is upregulated on CD4+ T cells following activation.TIGIT interacts with CD155, and mediates the interaction between natural killer cells or T lymphocytes with APC and fibroblasts and endothelial cells expressing PVR or PVR-like proteins.
NCBI Gene ID
100043314
Swiss Prot
P86176
Host
Mouse
Reactivity
Mouse
Clonality
Monoclonal
Clone
1G9
Conjugation
PE
Type
Primary Antibodies
Field of Research
Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Mouse IgG1, kappa
Specificity
The 1G9 monoclonal antibody specifically binds to the mouse TIGIT, expressed on the T helper cells.
Symbol
Tigit
NCBI Official Name
T cell immunoreceptor with Ig and ITIM domains
NCBI Organism
Mus musculus
Other Product Names
Vstm3, ENSMUSG00000071552, Tigit
Tested Applications
Flow
Physical Properties
Liquid
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