IFN gamma Antibody [XMG1.2]
Product Specifications
Background
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation.
NCBI Gene ID
15978
Swiss Prot
P01580
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Clone
XMG1.2
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity, Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=77-040
Fragment
Rat IgG1, kappa
Specificity
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties.
Symbol
Ifng
NCBI Official Name
Interferon gamma
NCBI Organism
Mus musculus
Other Product Names
Ifg, IFN-g, Ifng
Tested Applications
Flow, Functional Assays, IHC, IF, ELISA
Physical Properties
Liquid
Curated Selection
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