TIM3 Antibody [F38-2E2] (APC)
Product Specifications
Background
The F38-2E2 monoclonal antibody specifically reacts with human T cell immunoglobulin and mucin domain containing protein (TIM3), a transmembrane molecule found on monocytes, macrophages, dendritic cells, and activated T cell types such as Treg, Th1, and Th17. TIM3 can exist in soluble and membrane bound forms and the relevant ligand for the protein is Galectin-9. It plays a role in the creation of immunological tolerances, the secretion of Th1 and Th17 related cytokines, and HIV infection.
NCBI Gene ID
84868
Swiss Prot
Q8TDQ0
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
F38-2E2
Conjugation
APC
Type
Primary Antibodies
Field of Research
Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Mouse IgG1, kappa
Specificity
The F38-2E2 monoclonal antibody specifically reacts with human T cell immunoglobulin and mucin domain containing protein (TIM3), a transmembrane molecule found on monocytes, macrophages, dendritic cells, and activated T cell types such as Treg, Th1, and Th17.
Symbol
HAVCR2
NCBI Official Name
Hepatitis A virus cellular receptor 2
NCBI Organism
Homo sapiens
Other Product Names
TIM3, KIM-3, TIMD3, Tim-3, TIMD-3, HAVcr-2, HAVCR2
Tested Applications
Flow
Physical Properties
Liquid
Frequently Asked Questions
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