TLR4/MD-2 Complex Antibody [MTS510]
Product Specifications
Background
The MTS510 monoclonal antibody specifically reacts with the Toll-Like Receptor 4 (TLR-4) and MD-2 (LY96) molecular complex. The complex of TLR-4, MD-2, and CD14 regulates the innate immune system recognition of bacterial lipopolysaccharides (LPS) and is expressed on the surface of thioglycollate-elicited macrophages. The epitope that binds the MTS510 antibody is lost after LPS stimulation and the antibody can be used to co-immunoprecipitates MD-2 and TLR4.
NCBI Gene ID
21898
Swiss Prot
Q9QUK6
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Clone
MTS510
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Fragment
Rat IgG2a, kappa
Specificity
The MTS510 monoclonal antibody specifically reacts with the Toll-Like Receptor 4 (TLR-4) and MD-2 (LY96) molecular complex.
Symbol
Tlr4
NCBI Official Name
Toll-like receptor 4
NCBI Organism
Mus musculus
Other Product Names
Lps, Ly87, Ran/M1, Rasl2-8, Tlr4
Tested Applications
Flow, Functional Assays
Physical Properties
Liquid
Frequently Asked Questions
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