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Notch3 Antibody [HMN3-133] (APC)

Product Specifications

Background

The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein. After binding with its ligand, Notch3 receptor undergoes cleavage resulting in a Notch intracellular domain (NICD) molecule that eventually activates transcription in the nucleus. It is expressed on Treg cells and adult smooth muscle arterial cells.

NCBI Gene ID

18131

Swiss Prot

Q61982

Host

Hamster

Reactivity

Mouse

Clonality

Monoclonal

Clone

HMN3-133

Conjugation

APC

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=77-001

Fragment

Armenian Hamster IgG

Specificity

The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein.

Symbol

Notch3

NCBI Official Name

Notch 3

NCBI Organism

Mus musculus

Other Product Names

N3, hpbk, AW229011, Notch3

Tested Applications

Flow

Physical Properties

Liquid

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