Notch3 Antibody [HMN3-133] (APC)
Product Specifications
Background
The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein. After binding with its ligand, Notch3 receptor undergoes cleavage resulting in a Notch intracellular domain (NICD) molecule that eventually activates transcription in the nucleus. It is expressed on Treg cells and adult smooth muscle arterial cells.
NCBI Gene ID
18131
Swiss Prot
Q61982
Host
Hamster
Reactivity
Mouse
Clonality
Monoclonal
Clone
HMN3-133
Conjugation
APC
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Armenian Hamster IgG
Specificity
The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein.
Symbol
Notch3
NCBI Official Name
Notch 3
NCBI Organism
Mus musculus
Other Product Names
N3, hpbk, AW229011, Notch3
Tested Applications
Flow
Physical Properties
Liquid
Frequently Asked Questions
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