CD309 Antibody [Avas12a1] (PE)

Product Specifications

Background

The Avas12a1 monoclonal antibody specifically reacts with mouse CD309, also known as fetal liver kinase-1 (Flk-1) or the vascular endothelial growth factor receptor 2 (VEGFR2) . CD309 is a receptor for VEGF and VEGFC and is expressed in endothelial cells in embryonic and adult tissue and a requirement for the development of vascular endothelial and hematopoietic cells.

NCBI Gene ID

16542

Swiss Prot

P35918

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

Avas12a1

Conjugation

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Rat IgG2a, kappa

Specificity

The Avas12a1 monoclonal antibody specifically reacts with mouse CD309, also known as fetal liver kinase-1 (Flk-1) or the vascular endothelial growth factor receptor 2 (VEGFR2) .

Symbol

Kdr

NCBI Official Name

Kinase insert domain protein receptor

NCBI Organism

Mus musculus

Background Reference 01

Sekine, C., Moriyama, Y., Koyanagi, A., Koyama, N., Ogata, H., Okumura, K., Yagita, H. (2009) . Differential regulation of splenic CD8 dendritic cells and marginal zone B cells by Notch ligands.International immunology,21 (3), 295-301.

Background Reference 02

Yamaguchi, E., Chiba, S., Kumano, K., Kunisato, A., Takahashi, T., Takahashi, T., Hirai, H. (2002) . Expression of Notch ligands, Jagged1, 2 and Delta1 in antigen presenting cells in mice.Immunology letters,81 (1), 59-64.

Background Reference 03

Elyaman, W., Bradshaw, E. M., Wang, Y., Oukka, M., Kiviskk, P., Chiba, S., ... Khoury, S. J. (2007) . JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis.The Journal of Immunology,179 (9), 5990-5998.