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CD138 Antibody [DL-101] (PE)

Product Specifications

Background

The DL-101 monoclonal antibody specifically reacts with human CD138, a 85-92 kDA type I heparan sulfate proteoglycan. CD138 is known as Syndecan-1 and is expressed on pre-B cells, immature B cells, plasma cells, and malignant plasma cells, to the exclusion of mature circulating B cells. Syndecan-1 is also expressed on vascular smooth muscle, endothelial, neural, and embryonic mesenchymal cells. It is involved in cellular proliferation, cellular migration, and acts as an extracellular matrix receptor. Among the hematopoietic elements, CD138 is a useful marker for plasma cells.

NCBI Gene ID

6382

Swiss Prot

P18827

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

DL-101

Conjugation

PE

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=76-933

Fragment

Mouse IgG1, kappa

Specificity

The DL-101 monoclonal antibody specifically reacts with human CD138, a 85-92 kDA type I heparan sulfate proteoglycan.

Symbol

SDC1

NCBI Official Name

Syndecan 1

NCBI Organism

Homo sapiens

Background Reference 01

Kayagaki, N., Kawasaki, A., Ebata, T., Ohmoto, H., Ikeda, S., Inoue, S., ... Yagita, H. (1995) . Metalloproteinase-mediated release of human Fas ligand.The Journal of experimental medicine,182 (6), 1777-1783.

Background Reference 02

Oyaizu, N., Adachi, Y., Hashimoto, F., McCloskey, T. W., Hosaka, N., Kayagaki, N., ... Pahwa, S. (1997) . Monocytes express Fas ligand upon CD4 cross-linking and induce CD4+ T cells apoptosis: a possible mechanism of bystander cell death in HIV infection.The Journal of Immunology,158 (5), 2456-2463.

Background Reference 03

Villunger, A., Egle, A., Marschitz, I., Kos, M., Bck, G., Ludwig, H., ... Greil, R. (1997) . Constitutive expression of Fas (Apo-1/CD95) ligand on multiple myeloma cells: a potential mechanism of tumor-induced suppression of immune surveillance.Blood,90 (1), 12-20.

Other Product Names

SDC, CD138, SYND1, syndecan, SDC1

Tested Applications

Flow

Physical Properties

Liquid

Curated Selection

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