What is the catalog number for CD107a Antibody [H4A3] (PE)?

The catalog number for CD107a Antibody [H4A3] (PE) is 76-892.

What sizes are available for CD107a Antibody [H4A3] (PE)?

CD107a Antibody [H4A3] (PE) is available in the following size(s): 25 Tests.

Is CD107a Antibody [H4A3] (PE) in stock?

CD107a Antibody [H4A3] (PE) is currently made to order / not held in immediate stock. Contact us for lead time.

CD107a Antibody [H4A3] (PE)

Product Specifications

Background

The H4A3 monoclonal antibody specifically reacts with human CD107a, a heavily glycosylated type I membrane glycoprotein. CD107a is also known as Lysosomal-associated membrane protein 1 (LAMP-1) and is widely expressed intracellular antigen. It can be found on the surface of PHA-activated lymphocytes, activated platelets, cytotoxic T cells, NK cells, macrophages, epithelial cells, endothelial cells, and some tumor lines. CD107a is a ligand for E-selectin and galaptin and is reported to be involved in cell adhesion and tumor metastasis.

NCBI Gene ID

3916

Swiss Prot

P11279

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

H4A3

Conjugation

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The H4A3 monoclonal antibody specifically reacts with human CD107a, a heavily glycosylated type I membrane glycoprotein.

Symbol

LAMP1

NCBI Official Name

Lysosomal-associated membrane protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Chen, J. W., Cha, Y. I. N. G., Yuksel, K. U., Gracy, R. W., August, J. T. (1988) . Isolation and sequencing of a cDNA clone encoding lysosomal membrane glycoprotein mouse LAMP-1. Sequence similarity to proteins bearing onco-differentiation antigens.Journal of Biological Chemistry,263 (18), 8754-8758.

Background Reference 02

Grtzkau, A., Smorodchenko, A., Lippert, U., Kirchhof, L., Artuc, M., Henz, B. M. (2004) . LAMP‐1 and LAMP‐2, but not LAMP‐3, are reliable markers for activation‐induced secretion of human mast cells.Cytometry Part A,61 (1), 62-68.

Background Reference 03

Sarafian, V., Jadot, M., Foidart, J. M., Letesson, J. J., Van den Brule, F., Castronovo, V., ... Coninck, W. D. (1998) . Expression of Lamp‐1 and Lamp‐2 and their interactions with galectin‐3 in human tumor cells.International journal of cancer,75 (1), 105-111.