What is the catalog number for CD184 Antibody [2B11] (PE)?

The catalog number for CD184 Antibody [2B11] (PE) is 76-872.

What sizes are available for CD184 Antibody [2B11] (PE)?

CD184 Antibody [2B11] (PE) is available in the following size(s): 0.05 mg.

Is CD184 Antibody [2B11] (PE) in stock?

CD184 Antibody [2B11] (PE) is currently made to order / not held in immediate stock. Contact us for lead time.

CD184 Antibody [2B11] (PE)

Product Specifications

Background

The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor. It is expressed by astrocytes, B cells, T cells, monocytes, neutrophils, neurons, and hematopoietic cell types. CD184 is a coreceptor for X4 HIV-1.The monoclonal 2B11 antibody recognizes the amino terminus of CD184 and has functional activity.

NCBI Gene ID

12767

Swiss Prot

P70658

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

2B11

Conjugation

Type

Primary Antibodies

Field of Research

Stem Cell, Chemokines & Cytokines, Growth Factors

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Rat IgG2b, kappa

Specificity

The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor.

Symbol

Cxcr4

NCBI Official Name

Chemokine (C-X-C motif) receptor 4

NCBI Organism

Mus musculus

Background Reference 01

Pierelli, L., Bonanno, G., Rutella, S., Marone, M., Scambia, G., Leone, G. (2001) . CD105 (endoglin) expression on hematopoietic stem/progenitor cells.Leukemia lymphoma,42 (6), 1195-1206.

Background Reference 02

She, X., Matsuno, F., Harada, N., Tsai, H., Seon, B. K. (2004) . Synergy between anti‐endoglin (CD105) monoclonal antibodies and TGF‐-beta in suppression of growth of human endothelial cells.International journal of cancer,108 (2), 251-257.

Background Reference 03

Seon, B. K., Kumar, S. (2002) . CD105 antibody for targeting of tumor vascular endothelial cells. InThe new angiotherapy (pp. 499-515) . Humana Press.