What is the catalog number for CD161 Antibody [HP-3G10] (APC)?

The catalog number for CD161 Antibody [HP-3G10] (APC) is 76-841.

What sizes are available for CD161 Antibody [HP-3G10] (APC)?

CD161 Antibody [HP-3G10] (APC) is available in the following size(s): 25 Tests.

Is CD161 Antibody [HP-3G10] (APC) in stock?

CD161 Antibody [HP-3G10] (APC) is currently made to order / not held in immediate stock. Contact us for lead time.

CD161 Antibody [HP-3G10] (APC)

Product Specifications

Background

The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A. CD161 is expressed on most natural killer cells, subsets of CD4+ and CD8+ T lymphocytes, gammadelta TCR T lymphocytes, a subset of CD3+ thymocytes, and especially on CD45RO+ T lymphocytes. Reports indicate that it may serve as a specific receptor for some natural killer cell targets and a possible stimulatory role.

NCBI Gene ID

3820

Swiss Prot

Q12918

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

HP-3G10

Conjugation

APC

Type

Primary Antibodies

Field of Research

Innate Immunity, Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A.

Symbol

KLRB1

NCBI Official Name

Killer cell lectin-like receptor subfamily B, member 1

NCBI Organism

Homo sapiens

Background Reference 01

Barclay, A. N., Brown, M. H., Law, S. A. K. A., McKnight, A. J., Tomlinson, M. G., van der Merwe, P. A. (1997) .The leucocyte antigen factsbook. Academic Press.

Background Reference 02

Lindsten, T., Lee, K. P., Harris, E. S., Petryniak, B., Craighead, N., Reynolds, P. J., ... Gray, G. S. (1993) . Characterization of CTLA-4 structure and expression on human T cells.The Journal of Immunology,151 (7), 3489-3499.

Background Reference 03

Kuiper, H. M., Brouwer, M., Linsley, P. S., Van Lier, R. A. (1995) . Activated T cells can induce high levels of CTLA-4 expression on B cells.The Journal of Immunology,155 (4), 1776-1783.