What is the catalog number for CD161 Antibody [HP-3G10] (Violet-450)?

The catalog number for CD161 Antibody [HP-3G10] (Violet-450) is 76-833.

What sizes are available for CD161 Antibody [HP-3G10] (Violet-450)?

CD161 Antibody [HP-3G10] (Violet-450) is available in the following size(s): 25 Tests.

Is CD161 Antibody [HP-3G10] (Violet-450) in stock?

CD161 Antibody [HP-3G10] (Violet-450) is currently made to order / not held in immediate stock. Contact us for lead time.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

CD161 Antibody [HP-3G10] (Violet-450)

Product Specifications

Background

The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A. CD161 is expressed on most natural killer cells, subsets of CD4+ and CD8+ T lymphocytes, gammadelta TCR T lymphocytes, a subset of CD3+ thymocytes, and especially on CD45RO+ T lymphocytes. Reports indicate that it may serve as a specific receptor for some natural killer cell targets and a possible stimulatory role. BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

NCBI Gene ID

3820

Swiss Prot

Q12918

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

HP-3G10

Conjugation

Violet-450

Type

Primary Antibodies

Field of Research

Innate Immunity, Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A.

Symbol

KLRB1

NCBI Official Name

Killer cell lectin-like receptor subfamily B, member 1

NCBI Organism

Homo sapiens

Background Reference 01

Mrquez, C., Trigueros, C., Franco, J. M., Ramiro, A. R., Carrasco, Y. R., Lpez-Botet, M., Toribio, M. L. (1998) . Identification of a common developmental pathway for thymic natural killer cells and dendritic cells.Blood,91 (8), 2760-2771.

Background Reference 02

Cosmi, L., De Palma, R., Santarlasci, V., Maggi, L., Capone, M., Frosali, F., ... Annunziato, F. (2008) . Human interleukin 17producing cells originate from a CD161+ CD4+ T cell precursor.The Journal of experimental medicine,205 (8), 1903-1916.

Background Reference 03

Exley, M., Porcelli, S., Furman, M., Garcia, J., Balk, S. (1998) . CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Valpha 24Jalpha Q T cell receptor alpha chains.The Journal of experimental medicine,188 (5), 867-876.