CD105 Antibody [MJ7/18] (PE)
Product Specifications
Background
The MJ7/18 monoclonal antibody specifically reacts with mouse CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells. CD105 is a marker for tumor angiogenesis research by identifying proliferating endothelium. It is also suggested to be involved in embryonic angiogenesis and cellular adhesion.
NCBI Gene ID
13805
Swiss Prot
Q63961
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Clone
MJ7/18
Conjugation
PE
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Rat IgG2a, kappa
Specificity
The MJ7/18 monoclonal antibody specifically reacts with mouse CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells.
Symbol
Eng
NCBI Official Name
Endoglin
NCBI Organism
Mus musculus
Background Reference 01
Mrquez, C., Trigueros, C., Franco, J. M., Ramiro, A. R., Carrasco, Y. R., Lpez-Botet, M., Toribio, M. L. (1998) . Identification of a common developmental pathway for thymic natural killer cells and dendritic cells.Blood,91 (8), 2760-2771.
Background Reference 02
Cosmi, L., De Palma, R., Santarlasci, V., Maggi, L., Capone, M., Frosali, F., ... Annunziato, F. (2008) . Human interleukin 17producing cells originate from a CD161+ CD4+ T cell precursor.The Journal of experimental medicine,205 (8), 1903-1916.
Background Reference 03
Exley, M., Porcelli, S., Furman, M., Garcia, J., Balk, S. (1998) . CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Valpha 24Jalpha Q T cell receptor alpha chains.The Journal of experimental medicine,188 (5), 867-876.
Other Product Names
Endo, CD105, AI528660, AI662476, S-endoglin, Eng
Tested Applications
Flow
Physical Properties
Liquid
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